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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOLC1 All Species: 11.82
Human Site: T259 Identified Species: 20
UniProt: Q14978 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14978 NP_004732.2 699 73603 T259 A P V K A A T T P T R K S S S
Chimpanzee Pan troglodytes XP_001171017 700 73581 T260 A P V K A A A T P T R K S S S
Rhesus Macaque Macaca mulatta XP_001112196 701 73703 T260 A P V K A V A T P P Q K S S S
Dog Lupus familis XP_851848 704 74723 T263 S P V K A A A T T T Q K S S S
Cat Felis silvestris
Mouse Mus musculus O08784 1320 134983 G651 P V H T Q K T G P S V K A M A
Rat Rattus norvegicus P41777 704 73545 A269 A P V K V T A A P T Q K S S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511079 669 69188 P214 A A A K N A A P A A K K A A P
Chicken Gallus gallus XP_421630 694 72200 K241 Q S C P G K T K P A K E S S S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689627 1001 102013 A344 A P T K V A P A Q K K D S S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730693 686 70584 P219 K P V A K A A P A K K A A S S
Honey Bee Apis mellifera XP_001120943 685 75016 P235 L K K A T P I P P T K S T A K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796224 791 84162 V281 T P N K A K T V P V K K A E S
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001168628 517 55362 L94 S T R A A A I L G S D E Q D K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32583 406 40997
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 94.2 81.5 N.A. 24.9 74.1 N.A. 50.7 43.6 N.A. 36.6 N.A. 27.3 22 N.A. 34.5
Protein Similarity: 100 98.8 95.5 85.6 N.A. 36.7 81.2 N.A. 60.3 57.5 N.A. 47.5 N.A. 42.3 42.9 N.A. 47.9
P-Site Identity: 100 93.3 73.3 73.3 N.A. 20 66.6 N.A. 26.6 33.3 N.A. 46.6 N.A. 33.3 13.3 N.A. 46.6
P-Site Similarity: 100 93.3 80 86.6 N.A. 40 73.3 N.A. 46.6 46.6 N.A. 53.3 N.A. 46.6 33.3 N.A. 60
Percent
Protein Identity: N.A. 23.6 N.A. N.A. 25.1 N.A.
Protein Similarity: N.A. 40.9 N.A. N.A. 39.4 N.A.
P-Site Identity: N.A. 13.3 N.A. N.A. 0 N.A.
P-Site Similarity: N.A. 33.3 N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 8 8 22 43 50 43 15 15 15 0 8 29 15 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 8 0 8 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 15 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 8 8 0 0 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % I
% Lys: 8 8 8 58 8 22 0 8 0 15 43 58 0 0 15 % K
% Leu: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 58 0 8 0 8 8 22 58 8 0 0 0 0 8 % P
% Gln: 8 0 0 0 8 0 0 0 8 0 22 0 8 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 15 0 0 0 0 % R
% Ser: 15 8 0 0 0 0 0 0 0 15 0 8 50 58 65 % S
% Thr: 8 8 8 8 8 8 29 29 8 36 0 0 8 0 0 % T
% Val: 0 8 43 0 15 8 0 8 0 8 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _